Nmr With Biological Macromolecules In Solution: A Selection Of Papers Published From 1996 To 2020 By Kurt Wuthrich - Kurt Wuthrich - Grāmatas - World Scientific Publishing Co Pte Ltd - 9789811239137 - 2021. gada 3. novembris
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Nmr With Biological Macromolecules In Solution: A Selection Of Papers Published From 1996 To 2020 By Kurt Wuthrich


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The book provides insights into the research of the Kurt Wuthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones. Key publications from the Kurt Wuthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome , metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.

Mediji Grāmatas     Paperback Book   (Grāmata ar mīksto vāku un līmēto muguru)
Izlaists 2021. gada 3. novembris
ISBN13 9789811239137
Izdevēji World Scientific Publishing Co Pte Ltd
Lapas 264
Izmēri 191 × 259 × 13 mm   ·   612 g
Valoda Angļu  

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