Vladimir Zyabrev

Sintezy Azotistykh Geterotsiklov Na Osnove -galogenalkilamidov: Izbrannye Obzory Vladimir Zyabrev Russian edition

Azotistye geterotsikly igrayut fundamental'nuyu rol' vo mnogikh biologicheskikh protsessakh, sostavlyayut osnovu bol'shinstva sinteticheskikh lekarstvennykh preparatov, ispol'zuyutsya v proizvodstve pestitsidov, krasiteley, polimerov, yavlyayutsya ob"ektami nauchnykh issledovaniy. Dlya polucheniya funktsional'nozameshchennykh azageterotsiklov neobkhodimy dostupnye iskhodnye soedineniya, kotorye soderzhat neskol'ko reaktsionnykh tsentrov so spetsificheskoy aktivnost'yu. Tsel' monografii ? osvetit' sovremennoe sostoyanie khimii ryada politsentrovykh elektrofil'nykh reagentov, poluchayushchikhsya na osnove ?-galogenalkilamidov, i pokazat' ikh vazhnost' v sintezakh azotistykh geterotsiklov. K takim reagentam otnosyatsya N-(1,2,2,2-tetrakhloretil)amidy, ?-karbonil-?-galogenalkilamidy, ?-galogenzameshchennye alkilgeterokumuleny, nitrily s kharakternoy gruppirovkoy HlgC=CCN, nenasyshchennye azlaktony s podvizhnymi atomami ili gruppami v metilenovom ostatke, a takzhe produkty zameshcheniya atomov galogena v ?-galogenalkilamidakh na razlichnye serosoderzhashchie gruppy. Kniga prednaznachena dlya nauchnykh rabotnikov, prepodavateley i aspirantov, spetsializiruyushchikhsya v oblasti tonkogo organicheskogo sinteza i khimii geterotsiklov.