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Population Balance Modelling of Non-native Protein Aggregation: Kinetics of Protein Aggregation Peter Grancic
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Population Balance Modelling of Non-native Protein Aggregation: Kinetics of Protein Aggregation
Peter Grancic
A comprehensive modelling methodology for analysis of the kinetics of non-native protein aggregation based on general population balance model within the Extended Lumry-Eyring framework is presented. The population balance model is formulated in terms of key parameters, describing relative importance of (un)folding and aggregation kinetics of a protein in diffusion-driven conditions. Both the analytical and numerical solution provide a detailed insight on the intrinsic aggregation kinetics via time-dependent evolution of a variety of experimentally measurable quantities.
| Mediji | Grāmatas Paperback Book (Grāmata ar mīksto vāku un līmēto muguru) |
| Izlaists | 2012. gada 21. augusts |
| ISBN13 | 9783659212031 |
| Izdevēji | LAP LAMBERT Academic Publishing |
| Lapas | 108 |
| Izmēri | 150 × 7 × 226 mm · 179 g |
| Valoda | Vācu |
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