Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy - Recent Results in Cancer Research - Rainer Haas - Grāmatas - Springer-Verlag Berlin and Heidelberg Gm - 9783642468384 - 2012. gada 4. aprīlis
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Rainer Haas
Advances in Hematopoietic Stem Cell Transplantation and Molecular Therapy - Recent Results in Cancer Research Softcover reprint of the original 1st ed. 1998 edition

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Jacket Description/Back: This book gives an overview of the current state of the art in peripheral blood stem cell transplantation and recent developments in molecular diagnosis and gene therapeutic approaches. The focus is on the role of peripheral blood stem cell transplantation in the treatment of hematological malignancies such as non-Hodgkin lymphomas, chronic myelogenous leukemia and multiple myeloma. Current molecular biological techniques for detecting genetic defects in tumors and minimal residual disease are also presented. Further topics include new gene therapeutic concepts in hematology and oncology: the use of viral vectors for transduction of hematopoietic cells is discussed as well as therapeutic strategies based on antisense nucleic acids, ribozymes, and immunological approaches. Table of Contents: Mobilization and Selection of CD34+Cells.- Autologous Stem Cell Transplantation for Chronic Myeloid Leukemia.- Autologous Stem Cell Transplantation.- Peripheral Blood Progenitor Cell Transplantation.- Molecular Monitoring of Residual Disease.- Delineation of Genomic Regions in Chromosome Band 7q22 Commonly Deleted in Myeloid Leukemias.- Molecular Cytogenic Analysis of Low-Grade B-Cell Neoplasias: A Comparative Genomic Hybridization Study.- Applications of Gene Transfer in Hematologic Malignancy.- Dendritic Cells for Somatic Gene Therapy.- Construction of Immunogenetic Tumor Cell Surfaces by Somatic Gene Transfer.- Adeno-associated Virus Type 2 Vector for Transduction of Hematopoietic Cells.- Protection of Hematopoietic Stem Cells from Chemotherapy-Induced Toxicity by Multidrug-Resistance 1 Gene Transfer.- Regulated Gene Expression After Retroviral Vector-Mediated Delivery of Cancer-Relevant Therapeutic Genes.- Specific bcr-abl Directed Antisense Nucleic Acids and Ribozymes: A Tool for The Treatment of Chronic Myelogenous Leukemia?.- The Use of Ribozymes in Gene Therapy Approaches to AIDS.- Subject Index.-

150 pages, 8 black & white tables, biography

Mediji Grāmatas     Paperback Book   (Grāmata ar mīksto vāku un līmēto muguru)
Izlaists 2012. gada 4. aprīlis
ISBN13 9783642468384
Izdevēji Springer-Verlag Berlin and Heidelberg Gm
Lapas 150
Izmēri 155 × 235 × 8 mm   ·   240 g
Valoda Vācu  
Redaktors Haas, Rainer
Redaktors Kronenwett, Ralf
Redaktors Sczakiel, Georg

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