Meryl Brody

Metabolism in Cancer Meryl Brody

Cancer metabolism is an important area of research in cancer biology that is based on the principle that cancer cells have altered metabolic activities, which support the acquisition and maintenance of malignant properties. Research in this domain strives to understand the mechanism by which metabolism becomes reprogrammed in cancer cells and how such metabolic changes can be exploited for therapeutic benefit. An important theme in cancer metabolism is the cellular fitness provided by reprogrammed activities that enable a selective advantage during tumorigenesis. Due to this, cancer cells grow and proliferate at elevated levels, and survive under stressful conditions. Altered bioenergetics, redox balance and enhanced biosynthesis are some processes that provide benefit to the malignant cell and hence holds potential as therapeutic targets. This book includes some of the vital pieces of work being conducted across the world, on various topics related to cancer metabolism. It presents the complex subject of cancer metabolism in the most comprehensible language. It is meant for students who are looking for an elaborate reference text in this domain.