Abida Asmat

Laparoscopic Cholecystectomy: Role of Single Dose Dexamethasone: ?effect of Pre-operative Single Dose Dexamethasone in Patients Undergoing Laparoscopic Cholecystectomy? Abida Asmat

Laparoscopic cholecystectomy was first done by a French surgeon, Phillipe Mouret in 1987. It is one of the most common elective surgical procedure now-a- days. It has gained widespread acceptance as treatment of choice for cholelithiasis as it is associated with minimal morbidity and earlier return to work. Dexamethasone is well known for its anti-inflammatory, immune-modulating and anti- emetic effect. Dexamethasone is long acting (t half >36hrs) glucocorticoid. It is important modifier of the post-operative physiological inflammatory, humoral and immunological response by the regulation of the trauma induced humoral mechanism. I undertook present study to investigate in what way pre-operative intravenous administration of dexamethasone alters the surgical outcome in patients undergoing un- complicated laparoscopic cholecystectomy.