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Rational Drug Design of Substituted Analogues Angiotensin II Receptor: Statistical Approach Qsar for Group-specific Biological Activity Predictions; Different Series of Substituted Analogues Smita Sharma
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Rational Drug Design of Substituted Analogues Angiotensin II Receptor: Statistical Approach Qsar for Group-specific Biological Activity Predictions; Different Series of Substituted Analogues
Smita Sharma
Hypertension has become one of the most important preventable causes for premature morbidity and mortality worldwide. To identify novel and potent antihypertensive ligands, initially 2D-QSAR, Group based QSAR, kNN based 3D-QSAR and pharmacophore were generated using namely, a series of triazolinone, quinazolinone, and benzimidazole derivatives of as Angiotensin II AT1 Receptor. In conclusion, the models developed to predict the structural features of substituted analogues angiotensin II receptor antagonists, reveals useful information about the structural features requirement for the molecule.
| Mediji | Grāmatas Paperback Book (Grāmata ar mīksto vāku un līmēto muguru) |
| Izlaists | 2014. gada 23. maijs |
| ISBN13 | 9783659542961 |
| Izdevēji | LAP LAMBERT Academic Publishing |
| Lapas | 100 |
| Izmēri | 150 × 6 × 226 mm · 167 g |
| Valoda | Vācu |
