Antisense Research and Application - Handbook of Experimental Pharmacology - Agrawal - Grāmatas - Springer-Verlag Berlin and Heidelberg Gm - 9783540638339 - 1998. gada 16. aprīlis
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Antisense Research and Application - Handbook of Experimental Pharmacology 1998 edition

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Marc Notes: Includes bibliographical references and index. Table of Contents: 1 Basic Principles of Antisense Therapeutics.- 2 Antisense Medicinal Chemistry.- 3 In Vitro Cellular Uptake, Distribution, and Metabolism of Oligonucleotides.- 4 Pharmacokinetic Properties of Phosphorothioates in Animals Absorption, Distribution, Metabolism and Elimination.- 5 Toxicity of Oligodeoxynucleotide Therapeutic Agents.- 6 Pharmacokinetic Properties of Phosphorothioate Oligonucleotides in Immune Stimulation by Oligonucleotides in Humans.- 7 Safety and Tolerance of Phosphorothioates in Humans.- 8 Inmune Stimulation by Oligonucleotides.- 9 Pharmacological Inhibition of Dopaminergic and Other Neurotransmitter Receptors Using Antisense Oligodeoxynucleotides.- 10 Pharmacological Effects of Antisense Oligonucleotide Inhibition of Immediate-Early Response Genes in the CNS.- 11 Inhibition of G Proteins by Antisense Drugs.- 12 Use of Antisense Oligonucleotides to Modify Inflammatory Processes.- 13 Antisense Oligonucleotides and Their Anticancer Activities.- 14 Pharmacological Activity of Antisense Oligonucleotides in Animal Models of Disease.- 15 Clincial Antiviral Activities.- 16 Antisense Oligonucleotides to Protein Kinase C-a and C-raf Kinase: Rationale and Clinical Experience in Patients with Solid Tumors.- 17 Nucleic Acid Therapeutics for Human Leukemia: Development and Early Clinical Experience with Oligodeoxynucleotides Directed at c-myb.- 18 Properties of ISIS 2302, an Inhibitor of Intercellular Adhesion Molecule-1, Humans.- 19 Pharmacokinetics and Bioavailability of Antisense Oligonucleotides Following Oral and Colorectal Administrations in Experimental Animals.- 20 Antisense Properties of Peptide Nucleic Acid.- 21 Triple Helix Strategies and Progress."

Mediji Grāmatas     Hardcover Book   (Grāmata ar cieto muguriņu un vāku)
Izlaists 1998. gada 16. aprīlis
ISBN13 9783540638339
Izdevēji Springer-Verlag Berlin and Heidelberg Gm
Lapas 630
Izmēri 155 × 235 × 35 mm   ·   1,09 kg
Valoda Vācu  
Redaktors Crooke, Stanley T.

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